Carolina Miguel Gonçalvesa, Cátia Fariaa, Pedro Neves Tavaresa, Fátima Saraivaa, Maria Jesus Banzaa, João Moraisa,b
a Hospitalar de Leiria
b ciTechCare – Center for Innovative Care and Health Technology. Polytechnic of Leiria
Published: 25 September 2022
Introduction: Ischemic stroke is a leading cause of death and morbidity worldwide. There are multiple etiologies and, in rare cases, protein C and S deficiencies and meningioma may contribute to its occurrence.
Case description: A 39-year-old woman, with past medical history of meningioma, presented with 1-day history of dysarthria, right facial palsy and sensation loss of the right hand (National Institute of Health Stroke Scale (NIHSS) of 3 points). Head computed tomography reported a left middle cerebral artery stroke and she was hospitalized. Etiologic investigations revealed decreased levels of protein C and S and head magnetic resonance imaging revealed a meningioma extending into left cavernous sinus meningioma with internal carotid stenosis. During hospital stay her neurological deficits resolved completely and she was started in high dose statin and long-term therapeutic anticoagulation.
Discussion Whereas thrombophilias are associated with increased venous thromboembolism, its association with arterial events is controversial, despite several cases reported. Similarly, meningiomas are rarely associated with stroke. Etiologic investigations in cases of stroke in young individuals are essential to provide the best care to these patients.
Subject area: Secondary prevention of cardiovascular disease
Centro Hospitalar de Leiria
Centro Hospitalar de Leiria
Centro Hospitalar de Leiria
Centro Hospitalar de Leiria
Centro Hospitalar de Leiria
Centro Hospitalar de Leiria
ciTechCare – Center for Innovative Care and Health Technology. Polytechnic of Leiria
Correspondence to [email protected]
Subject area: Secondary prevention of cardiovascular disease
For questions about clinical cases submissions, please contact:
[email protected]
For technical assistance at any step of the process, or bug report, please contact:
[email protected]